Kids Research Express

Hormones from the endocrine organs are secreted directly into the bloodstream, where special proteins usually bind to them, helping to keep the hormones intact as they travel throughout the body. The proteins also act as a reservoir, allowing only a small fraction of the hormone circulating in the blood to affect the target tissue. Specialized proteins in the target tissue, called receptors, bind with the hormones in the bloodstream, inducing chemical changes in response to the body’s needs. Typically, only minute concentrations of a hormone are needed to achieve the desired effect. Too much or too little hormone can be harmful to the body, so hormone levels are regulated by a feedback mechanism. Feedback works something like a household thermostat. When the heat in a house falls, the thermostat responds by switching the furnace on, and when the temperature is too warm, the thermostat switches the furnace off. Usually, the change that a hormone produces also serves to regulate that hor...

. The primary glands that make up the human endocrine system are the hypothalamus , pituitary , thyroid , parathyroid , adrenal , pineal body , and reproductive glands—the ovary and testis . The pancreas , an organ often associated with the digestive system, is also considered part of the endocrine system. In addition, some nonendocrine organs are known to actively secrete hormones. These include the brain, heart, lungs, kidneys, liver, thymus, skin, and placenta. Almost all body cells can either produce or convert hormones, and some secrete hormones. For example, glucagon, a hormone that raises glucose levels in the blood when the body needs extra energy, is made in the pancreas but also in the wall of the gastrointestinal tract. However, it is the endocrine glands that are specialized for hormone production. They efficiently manufacture chemically complex hormones from simple chemical substances—for example, amino acids and carbohydrates—and they regulate their secretion more effici...

. Endocrine System, group of specialized organs and body tissues that produce, store, and secrete chemical substances known as hormones . As the body's chemical messengers, hormones transfer information and instructions from one set of cells to another. Because of the hormones they produce, endocrine organs have a great deal of influence over the body. Among their many jobs are regulating the body's growth and development, controlling the function of various tissues, supporting pregnancy and other reproductive functions, and regulating metabolism . Endocrine organs are sometimes called ductless glands because they have no ducts connecting them to specific body parts. The hormones they secrete are released directly into the bloodstream. In contrast, the exocrine glands, such as the sweat glands or the salivary glands, release their secretions directly to target areas—for example, the skin or the inside of the mouth. Some of the body's glands are described as endo-exocrine gl...